TB-Profiler result

Run: ERR4818494
Summary

Run ID: ERR4818494

Sample name:

Date: 01-04-2023 15:35:25

Number of reads: 991582

Percentage reads mapped: 98.92

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 763310 c.-60C>A upstream_gene_variant 0.11
rpoC 766170 p.Gly934Asp missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778643 p.Trp88* stop_gained 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1406551 p.Leu264Met missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472777 n.932G>T non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474289 n.632C>A non_coding_transcript_exon_variant 0.5
rrl 1476019 n.2362G>A non_coding_transcript_exon_variant 0.33
inhA 1675008 c.807C>A synonymous_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519038 c.924C>G synonymous_variant 0.13
thyA 3074407 p.Thr22Asn missense_variant 0.15
fbiA 3640904 p.Ala121Val missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245655 p.Asp808Val missense_variant 0.14
aftB 4267095 p.Pro581Gln missense_variant 0.11
aftB 4267329 p.Arg503Leu missense_variant 0.18
aftB 4267645 p.Asp398Asn missense_variant 0.17
aftB 4267759 p.Gly360Cys missense_variant 0.18
ubiA 4269104 p.Ser244Gly missense_variant 0.1
ethA 4328034 c.-561C>G upstream_gene_variant 1.0
ethA 4328404 c.-931T>G upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0