TB-Profiler result

Run: ERR4818549
Summary

Run ID: ERR4818549

Sample name:

Date: 01-04-2023 15:37:19

Number of reads: 1001913

Percentage reads mapped: 99.84

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 759620 c.-187A>C upstream_gene_variant 0.2
Rv1258c 1407415 c.-84_-76delCGAACATCC upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473386 n.-272G>A upstream_gene_variant 0.18
rrl 1475241 n.1584C>T non_coding_transcript_exon_variant 0.29
rrl 1475301 n.1644T>C non_coding_transcript_exon_variant 0.22
fabG1 1673560 p.Lys41Leu missense_variant 0.11
ahpC 2726338 p.Val49Gly missense_variant 0.29
fbiD 3339744 c.627A>C synonymous_variant 0.12
embA 4244773 p.Ser514* stop_gained 0.12
embB 4246544 p.Thr11Pro missense_variant 0.12
embB 4246548 p.Pro12Gln missense_variant 0.12
embB 4246555 c.42G>C synonymous_variant 0.12
embB 4246556 p.Ala15Pro missense_variant 0.12
embB 4246563 p.Leu17Trp missense_variant 0.12
embB 4246567 c.54G>T synonymous_variant 0.12