TB-Profiler result

Run: ERR4818695
Summary

Run ID: ERR4818695

Sample name:

Date: 01-04-2023 15:42:05

Number of reads: 810991

Percentage reads mapped: 99.51

Strain: lineage4.6.4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.4 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491598 c.816C>T synonymous_variant 1.0
mshA 576424 c.1077T>C synonymous_variant 0.12
rpoB 762478 p.Lys891Arg missense_variant 0.12
rpoC 762483 c.-887C>T upstream_gene_variant 0.11
mmpL5 775624 p.Pro953Ser missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777905 c.576G>A synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473481 n.-177C>A upstream_gene_variant 0.12
rrl 1474750 n.1093C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222015 p.Val384Ile missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726687 c.495C>A synonymous_variant 0.12
fbiD 3339589 p.Leu158Val missense_variant 0.14
Rv3083 3449350 p.Met283Val missense_variant 0.15
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
ddn 3987116 c.273C>T synonymous_variant 1.0
embC 4240801 c.939C>T synonymous_variant 0.12
embC 4240803 p.Tyr314Phe missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244472 p.Val414Met missense_variant 0.22
embB 4248580 c.2067G>A synonymous_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0