TB-Profiler result

Run: ERR4819126
Summary

Run ID: ERR4819126

Sample name:

Date: 01-04-2023 15:56:18

Number of reads: 1404973

Percentage reads mapped: 99.79

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5852 p.Thr205Ser missense_variant 0.11
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619762 c.-129C>G upstream_gene_variant 1.0
rpoC 765718 c.2349C>T synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917814 c.-126C>G upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154436 p.Ala559Asp missense_variant 0.12
PPE35 2168835 p.Pro593Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065301 c.891C>T synonymous_variant 0.12
thyA 3074353 p.Ala40Val missense_variant 0.11
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
rpoA 3878475 p.Glu11Asp missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328261 c.-788C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0