TB-Profiler result

Run: ERR4819280
Summary

Run ID: ERR4819280

Sample name:

Date: 01-04-2023 16:01:25

Number of reads: 243141

Percentage reads mapped: 72.31

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.4
gyrA 6742 c.-560A>G upstream_gene_variant 0.4
gyrA 6745 c.-557T>G upstream_gene_variant 0.4
gyrA 6751 c.-551G>C upstream_gene_variant 0.4
gyrB 6754 c.1516delA frameshift_variant 0.33
gyrA 6760 c.-542G>C upstream_gene_variant 0.33
gyrA 6763 c.-539G>C upstream_gene_variant 0.33
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7427 c.126G>C synonymous_variant 0.33
gyrA 7442 c.141G>C synonymous_variant 0.5
gyrA 7451 c.150C>G synonymous_variant 0.4
gyrA 7457 c.156T>C synonymous_variant 0.33
gyrA 7475 c.174A>G synonymous_variant 0.33
gyrA 7480 p.Phe60Tyr missense_variant 0.4
gyrA 7484 c.183T>C synonymous_variant 0.4
gyrA 7514 c.213C>G synonymous_variant 0.4
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7637 c.336C>G synonymous_variant 0.2
gyrA 7658 c.357A>G synonymous_variant 0.33
gyrA 7664 c.363T>C synonymous_variant 0.33
gyrA 7670 c.369A>G synonymous_variant 0.4
gyrA 7676 c.375G>C synonymous_variant 0.4
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 0.4
gyrA 7694 c.393A>G synonymous_variant 0.5
gyrA 7697 c.396C>A synonymous_variant 0.67
gyrA 8666 c.1365G>C synonymous_variant 0.4
gyrA 8693 c.1392T>C synonymous_variant 0.67
gyrA 8694 c.1393C>T synonymous_variant 0.67
gyrA 8711 c.1410A>C synonymous_variant 1.0
gyrA 8723 c.1422G>A synonymous_variant 1.0
gyrA 8729 c.1428T>C synonymous_variant 0.67
gyrA 8732 c.1431G>C synonymous_variant 0.67
gyrA 8786 c.1485T>C synonymous_variant 0.67
gyrA 8801 c.1500G>C synonymous_variant 0.4
gyrA 8807 c.1506C>T synonymous_variant 0.4
gyrA 8810 c.1509A>G synonymous_variant 0.4
gyrA 8816 c.1515C>G synonymous_variant 0.5
gyrA 8818 p.Ser506Asn missense_variant 0.5
gyrA 8828 c.1527T>C synonymous_variant 0.6
gyrA 8829 c.1528T>C synonymous_variant 0.5
gyrA 8852 c.1551T>C synonymous_variant 0.4
gyrA 8867 c.1566A>G synonymous_variant 0.5
gyrA 8870 c.1569G>C synonymous_variant 0.5
gyrA 8873 c.1572A>C synonymous_variant 0.5
gyrA 8891 c.1590G>A synonymous_variant 0.4
gyrA 8897 c.1596T>C synonymous_variant 0.5
gyrA 8903 c.1602T>C synonymous_variant 0.67
gyrA 9200 c.1899A>G synonymous_variant 0.5
gyrA 9204 p.Ser635Thr missense_variant 0.5
gyrA 9218 c.1917C>T synonymous_variant 0.5
gyrA 9227 c.1926C>G synonymous_variant 0.5
gyrA 9230 c.1929T>C synonymous_variant 0.5
gyrA 9233 c.1932C>G synonymous_variant 0.5
gyrA 9293 c.1992G>C synonymous_variant 0.5
gyrA 9296 c.1995T>C synonymous_variant 0.67
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490800 c.18A>C synonymous_variant 0.5
fgd1 490803 c.21T>A synonymous_variant 0.5
fgd1 490812 c.30A>G synonymous_variant 0.5
fgd1 490815 c.33G>C synonymous_variant 0.5
fgd1 490827 c.45C>T synonymous_variant 0.6
fgd1 490848 c.66A>G synonymous_variant 1.0
fgd1 490851 c.69A>T synonymous_variant 1.0
fgd1 490868 p.Ala29Gly missense_variant 1.0
fgd1 491535 c.753G>C synonymous_variant 0.33
fgd1 491542 c.760T>C synonymous_variant 0.25
fgd1 491547 c.765A>C synonymous_variant 0.29
fgd1 491550 c.768T>C synonymous_variant 0.33
fgd1 491553 c.771G>A synonymous_variant 0.29
fgd1 491601 c.819T>C synonymous_variant 0.2
fgd1 491610 c.828A>G synonymous_variant 0.22
fgd1 491616 c.834A>G synonymous_variant 0.22
fgd1 491620 p.Ile280Val missense_variant 0.22
mshA 575809 c.462C>T synonymous_variant 0.6
mshA 575812 c.465C>T synonymous_variant 0.75
mshA 575821 c.474G>C synonymous_variant 0.75
mshA 575824 c.477T>G synonymous_variant 0.75
mshA 575830 c.483C>G synonymous_variant 0.6
mshA 575833 c.486C>G synonymous_variant 0.6
mshA 575845 c.498C>T synonymous_variant 0.6
mshA 575884 c.537G>C synonymous_variant 0.5
mshA 575887 c.540G>C synonymous_variant 0.4
mshA 575893 c.546C>G synonymous_variant 0.4
mshA 575896 c.549G>C synonymous_variant 0.29
ccsA 620184 c.294C>A synonymous_variant 0.25
ccsA 620225 p.Glu112Gly missense_variant 0.25
ccsA 620424 c.534G>C synonymous_variant 0.18
rpoB 760724 c.918T>C synonymous_variant 1.0
rpoB 760730 c.924T>C synonymous_variant 1.0
rpoB 760751 c.945G>C synonymous_variant 1.0
rpoB 760757 c.951T>C synonymous_variant 1.0
rpoB 760759 p.Val318Ala missense_variant 1.0
rpoB 760769 c.963C>G synonymous_variant 0.5
rpoB 760775 c.969G>C synonymous_variant 0.5
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.5
rpoB 760793 c.987A>G synonymous_variant 0.33
rpoB 760805 c.999G>C synonymous_variant 0.33
rpoB 760982 c.1176G>C synonymous_variant 0.67
rpoB 760985 c.1179G>C synonymous_variant 0.67
rpoB 760991 c.1185G>C synonymous_variant 0.67
rpoB 761006 c.1200C>G synonymous_variant 0.67
rpoB 761015 c.1209G>C synonymous_variant 0.67
rpoB 761021 c.1215G>C synonymous_variant 0.67
rpoB 761027 c.1221A>G synonymous_variant 0.75
rpoB 761036 c.1230G>C synonymous_variant 0.75
rpoB 761037 c.1231T>C synonymous_variant 0.75
rpoB 761057 c.1251G>C synonymous_variant 0.6
rpoB 761180 c.1374A>C synonymous_variant 1.0
rpoB 761189 c.1383T>C synonymous_variant 1.0
rpoB 761195 c.1389G>C synonymous_variant 1.0
rpoB 761207 c.1401C>T synonymous_variant 1.0
rpoB 761213 c.1407G>C synonymous_variant 1.0
rpoB 761219 c.1413G>C synonymous_variant 1.0
rpoB 761249 c.1443A>G synonymous_variant 1.0
rpoB 761255 c.1449T>G synonymous_variant 0.67
rpoB 761261 c.1455G>T synonymous_variant 0.67
rpoB 761312 c.1506G>C synonymous_variant 0.67
rpoB 761327 c.1521A>G synonymous_variant 0.75
rpoB 761330 c.1524G>C synonymous_variant 0.75
rpoB 761354 c.1548C>T synonymous_variant 1.0
rpoB 761360 c.1554T>C synonymous_variant 1.0
rpoB 761362 p.Ser519Thr missense_variant 1.0
rpoB 761373 p.Val523His missense_variant 1.0
rpoB 761492 c.1686G>C synonymous_variant 1.0
rpoB 761510 c.1704T>C synonymous_variant 0.67
rpoB 761537 c.1731C>G synonymous_variant 0.67
rpoB 761606 c.1800C>G synonymous_variant 0.33
rpoB 761612 c.1806G>C synonymous_variant 0.5
rpoB 761615 c.1809A>C synonymous_variant 0.5
rpoB 761636 c.1830G>T synonymous_variant 0.5
rpoB 761645 c.1839C>G synonymous_variant 0.5
rpoB 761648 c.1842T>C synonymous_variant 0.67
rpoB 761657 c.1851C>G synonymous_variant 0.67
rpoB 761675 c.1869G>C synonymous_variant 0.43
rpoB 762197 c.2391C>T synonymous_variant 0.33
rpoB 762266 c.2460T>C synonymous_variant 0.5
rpoB 762284 c.2478G>C synonymous_variant 0.5
rpoB 762293 c.2487T>C synonymous_variant 0.5
rpoB 762317 c.2511A>G synonymous_variant 0.5
rpoB 762329 c.2523G>C synonymous_variant 0.5
rpoB 762338 c.2532T>C synonymous_variant 0.4
rpoB 762347 c.2541T>C synonymous_variant 0.4
rpoB 762362 p.Glu852Asp missense_variant 0.5
rpoB 762369 c.2563T>C synonymous_variant 0.67
rpoC 762926 c.-444C>T upstream_gene_variant 0.67
rpoC 762929 c.-441G>C upstream_gene_variant 0.67
rpoC 762989 c.-381G>C upstream_gene_variant 0.88
rpoC 762995 c.-375G>T upstream_gene_variant 0.88
rpoC 763013 c.-357C>G upstream_gene_variant 0.57
rpoC 763025 c.-345C>T upstream_gene_variant 0.75
rpoC 763028 c.-342T>C upstream_gene_variant 0.75
rpoC 763031 c.-339T>G upstream_gene_variant 0.75
rpoC 763034 c.-336C>G upstream_gene_variant 0.6
rpoC 763040 c.-330C>G upstream_gene_variant 0.6
rpoC 763070 c.-300T>C upstream_gene_variant 0.67
rpoC 763085 c.-285C>G upstream_gene_variant 0.6
rpoC 763115 c.-255T>C upstream_gene_variant 0.67
rpoC 763136 c.-234C>T upstream_gene_variant 0.8
rpoC 763148 c.-222G>C upstream_gene_variant 0.6
rpoC 764172 p.Phe268Tyr missense_variant 0.4
rpoC 764338 c.969G>A synonymous_variant 0.29
rpoC 764353 c.984G>C synonymous_variant 0.25
rpoC 764365 c.996C>T synonymous_variant 0.25
rpoC 764389 p.Leu340Phe missense_variant 0.33
rpoC 764593 c.1224C>T synonymous_variant 0.67
rpoC 764611 c.1242G>T synonymous_variant 0.5
rpoC 764650 c.1281G>C synonymous_variant 0.6
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.6
rpoC 764752 c.1383G>C synonymous_variant 0.43
rpoC 764764 c.1395T>C synonymous_variant 0.5
rpoC 764809 c.1440C>T synonymous_variant 1.0
rpoC 764815 c.1446A>G synonymous_variant 1.0
rpoC 764827 c.1458G>C synonymous_variant 1.0
rpoC 764858 c.1489T>C synonymous_variant 1.0
rpoC 764872 c.1503A>G synonymous_variant 1.0
rpoC 764888 c.1519T>C synonymous_variant 1.0
rpoC 764911 c.1542A>G synonymous_variant 0.5
rpoC 764932 c.1563C>A synonymous_variant 0.6
rpoC 764935 c.1566T>C synonymous_variant 0.6
rpoC 764948 c.1579T>C synonymous_variant 0.6
rpoC 764968 c.1599T>C synonymous_variant 0.5
rpoC 765700 c.2331T>C synonymous_variant 0.5
rpoC 765811 c.2442T>C synonymous_variant 1.0
rpoC 765814 c.2445A>G synonymous_variant 1.0
rpoC 765826 c.2457T>C synonymous_variant 1.0
rpoC 765835 c.2466C>T synonymous_variant 1.0
rpoC 765850 c.2481G>C synonymous_variant 0.8
rpoC 765883 c.2514C>G synonymous_variant 0.57
rpoC 765886 c.2517C>G synonymous_variant 0.57
rpoC 765892 c.2523T>C synonymous_variant 0.57
rpoC 766765 c.3396A>C synonymous_variant 0.5
rpoC 766774 c.3405T>C synonymous_variant 0.44
rpoC 766801 c.3432C>G synonymous_variant 0.29
rpoC 766804 c.3435A>G synonymous_variant 0.29
rpoC 766963 c.3594T>C synonymous_variant 0.15
rpoC 766972 c.3603G>C synonymous_variant 0.18
rpoC 766996 c.3627C>T synonymous_variant 0.22
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.33
rpoC 767014 c.3645G>C synonymous_variant 0.33
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.42
rpoC 767059 c.3690T>G synonymous_variant 0.33
rpoC 767062 c.3693C>A synonymous_variant 0.4
rpoC 767098 c.3729T>C synonymous_variant 0.3
rpoC 767119 c.3750A>G synonymous_variant 0.22
rpoC 767134 c.3765C>A synonymous_variant 0.33
rpoC 767158 c.3789T>C synonymous_variant 0.43
rpoC 767180 p.Ala1271Gln missense_variant 0.33
rpoC 767191 c.3822C>G synonymous_variant 0.33
rpoC 767206 c.3837C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777085 p.Asn466Asp missense_variant 0.22
mmpL5 777095 c.1386T>C synonymous_variant 0.22
mmpL5 777101 c.1380C>G synonymous_variant 0.18
mmpL5 777110 c.1371T>G synonymous_variant 0.17
mmpL5 777115 p.Met456Leu missense_variant 0.18
mmpL5 777116 c.1365C>T synonymous_variant 0.18
mmpL5 777133 p.Val450Ile missense_variant 0.18
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781608 p.Ser17Gly missense_variant 0.25
rpsL 781631 c.72G>C synonymous_variant 0.67
rpsL 781649 c.90T>C synonymous_variant 0.75
rpsL 781655 c.96T>C synonymous_variant 0.67
rpsL 781728 c.169T>C synonymous_variant 0.33
rpsL 781736 c.177T>C synonymous_variant 0.33
rpsL 781808 c.249C>T synonymous_variant 0.75
rpsL 781811 c.252C>T synonymous_variant 1.0
rpsL 781832 c.273T>C synonymous_variant 1.0
rpsL 781838 c.279G>C synonymous_variant 1.0
rpsL 781841 c.282C>G synonymous_variant 1.0
rplC 800715 c.-94A>C upstream_gene_variant 0.15
rplC 800720 c.-89T>C upstream_gene_variant 0.15
rplC 800723 c.-86C>G upstream_gene_variant 0.15
rplC 800747 c.-62C>G upstream_gene_variant 0.2
rplC 800907 c.99C>G synonymous_variant 0.22
rplC 800916 c.108A>G synonymous_variant 0.22
rplC 801195 c.387G>C synonymous_variant 0.33
rplC 801207 c.399C>T synonymous_variant 0.33
rplC 801246 c.438C>T synonymous_variant 0.4
rplC 801249 c.441T>C synonymous_variant 0.4
rplC 801255 c.447C>T synonymous_variant 0.5
rplC 801264 c.456C>T synonymous_variant 0.5
rplC 801267 c.459A>T synonymous_variant 0.5
rplC 801270 c.462T>C synonymous_variant 0.5
rplC 801276 c.468G>C synonymous_variant 0.5
rplC 801279 c.471G>C synonymous_variant 0.5
rplC 801282 c.474G>C synonymous_variant 0.5
rplC 801285 c.477G>C synonymous_variant 0.29
rplC 801367 p.Ala187Thr missense_variant 0.25
rplC 801402 c.594T>C synonymous_variant 0.29
rplC 801405 c.597T>C synonymous_variant 0.29
fbiC 1303575 c.645G>C synonymous_variant 0.4
fbiC 1303590 c.660A>G synonymous_variant 0.33
fbiC 1303602 c.672A>G synonymous_variant 0.33
fbiC 1303605 c.675C>G synonymous_variant 0.33
fbiC 1303608 c.678G>A synonymous_variant 0.33
fbiC 1303614 c.684C>T synonymous_variant 0.33
fbiC 1303617 c.687C>G synonymous_variant 0.22
fbiC 1303632 c.702T>G synonymous_variant 0.25
fbiC 1303641 c.711C>T synonymous_variant 0.25
fbiC 1303785 c.855G>C synonymous_variant 0.6
fbiC 1303789 p.Ile287Val missense_variant 0.67
fbiC 1303797 c.867A>G synonymous_variant 0.4
fbiC 1303818 c.888C>G synonymous_variant 0.5
fbiC 1303836 c.906G>C synonymous_variant 0.6
fbiC 1303845 c.915C>G synonymous_variant 0.5
fbiC 1303846 p.Phe306Val missense_variant 0.5
fbiC 1303854 c.924T>C synonymous_variant 0.5
fbiC 1303860 c.930A>C synonymous_variant 0.5
fbiC 1304703 c.1773C>G synonymous_variant 1.0
fbiC 1304711 p.Ala594Glu missense_variant 1.0
fbiC 1304715 c.1785G>C synonymous_variant 1.0
fbiC 1304724 c.1794A>G synonymous_variant 1.0
fbiC 1304727 c.1797A>G synonymous_variant 1.0
fbiC 1304739 c.1809C>T synonymous_variant 1.0
fbiC 1304742 c.1812T>C synonymous_variant 0.6
fbiC 1304757 c.1827A>G synonymous_variant 0.6
fbiC 1304778 c.1848T>C synonymous_variant 0.5
fbiC 1304784 c.1854T>C synonymous_variant 0.5
fbiC 1304787 c.1857T>G synonymous_variant 0.5
fbiC 1305372 c.2442G>A synonymous_variant 0.4
fbiC 1305384 c.2454G>C synonymous_variant 0.5
fbiC 1305396 c.2466C>G synonymous_variant 0.5
fbiC 1305405 c.2475A>G synonymous_variant 0.4
fbiC 1305417 c.2487C>G synonymous_variant 0.5
Rv1258c 1407538 c.-199delC upstream_gene_variant 0.2
embR 1417513 c.-166A>T upstream_gene_variant 0.2
atpE 1461206 p.Phe54Leu missense_variant 0.29
rrs 1471749 n.-97C>T upstream_gene_variant 0.67
fabG1 1673327 c.-113A>G upstream_gene_variant 0.29
inhA 1674896 p.Met232Thr missense_variant 0.25
rpsA 1833838 c.297G>C synonymous_variant 0.5
rpsA 1833841 c.300C>G synonymous_variant 0.5
rpsA 1833847 c.306C>G synonymous_variant 0.6
rpsA 1833856 c.315A>G synonymous_variant 0.75
rpsA 1833874 c.333T>C synonymous_variant 0.71
rpsA 1833886 c.345C>G synonymous_variant 0.71
rpsA 1833928 c.387G>C synonymous_variant 0.43
rpsA 1833940 c.399C>G synonymous_variant 0.5
rpsA 1833971 c.430C>T synonymous_variant 0.33
rpsA 1833979 c.438T>C synonymous_variant 0.38
rpsA 1834000 c.459G>C synonymous_variant 0.29
rpsA 1834021 c.480C>T synonymous_variant 0.33
rpsA 1834030 c.489C>G synonymous_variant 0.33
rpsA 1834366 c.825A>G synonymous_variant 0.2
rpsA 1834396 c.855G>C synonymous_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918389 c.450G>C synonymous_variant 0.21
tlyA 1918392 c.453A>C synonymous_variant 0.21
tlyA 1918422 c.483T>C synonymous_variant 0.27
tlyA 1918425 c.486C>A synonymous_variant 0.27
tlyA 1918434 c.495C>G synonymous_variant 0.2
tlyA 1918442 p.Val168Ala missense_variant 0.2
ndh 2102218 c.825C>A synonymous_variant 1.0
ndh 2102227 c.816C>T synonymous_variant 1.0
ndh 2102230 c.813G>C synonymous_variant 1.0
ndh 2102233 c.810G>A synonymous_variant 1.0
PPE35 2169624 p.Gly330Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288758 p.Gly162Ser missense_variant 0.4
ahpC 2726210 c.18T>C synonymous_variant 1.0
folC 2746468 c.1131G>C synonymous_variant 0.25
folC 2747745 c.-147A>C upstream_gene_variant 0.29
folC 2747751 c.-154_-153delGCinsCG upstream_gene_variant 0.25
folC 2747759 c.-161T>C upstream_gene_variant 0.22
folC 2747760 c.-162G>T upstream_gene_variant 0.22
folC 2747772 c.-174C>G upstream_gene_variant 0.29
folC 2747790 c.-192G>C upstream_gene_variant 0.29
ribD 2987140 p.Val101Ala missense_variant 0.29
ribD 2987165 c.327A>C synonymous_variant 0.29
ribD 2987168 c.330C>G synonymous_variant 0.29
ribD 2987177 c.339A>G synonymous_variant 0.29
Rv2752c 3065028 p.Val388Ile missense_variant 0.4
Rv2752c 3065040 c.1152C>G synonymous_variant 0.29
Rv2752c 3065048 c.1144C>T synonymous_variant 0.29
Rv2752c 3065052 c.1140G>A synonymous_variant 0.29
Rv2752c 3065055 c.1137T>C synonymous_variant 0.29
Rv2752c 3065064 c.1128G>C synonymous_variant 0.25
Rv2752c 3065073 c.1119C>G synonymous_variant 0.25
Rv2752c 3065079 c.1113T>C synonymous_variant 0.25
Rv2752c 3065082 c.1110G>C synonymous_variant 0.25
Rv2752c 3065087 c.1105A>C synonymous_variant 0.22
Rv2752c 3065088 c.1104A>G synonymous_variant 0.22
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 0.29
Rv2752c 3065115 c.1077C>A synonymous_variant 0.29
Rv2752c 3065183 p.Ser337Ala missense_variant 0.33
Rv2752c 3065186 c.1006T>C synonymous_variant 0.29
Rv2752c 3065223 c.969T>C synonymous_variant 0.38
Rv2752c 3065229 c.963G>C synonymous_variant 0.33
Rv2752c 3065232 c.960T>C synonymous_variant 0.4
Rv2752c 3065241 c.951A>G synonymous_variant 0.5
Rv2752c 3065262 c.930G>A synonymous_variant 0.45
Rv2752c 3065268 c.924A>G synonymous_variant 0.4
Rv2752c 3065288 c.904T>C synonymous_variant 0.25
Rv2752c 3065292 c.900T>C synonymous_variant 0.29
Rv2752c 3065295 p.Gln299Arg missense_variant 0.29
Rv2752c 3065298 p.Asp298Glu missense_variant 0.33
Rv2752c 3065306 p.Ala296Pro missense_variant 0.33
Rv2752c 3065311 p.Thr294Met missense_variant 0.33
Rv2752c 3065313 c.879A>G synonymous_variant 0.33
Rv2752c 3065323 p.Ala290Gly missense_variant 0.33
Rv2752c 3065675 p.Phe173Leu missense_variant 0.29
Rv2752c 3066102 c.90C>T synonymous_variant 0.22
Rv2752c 3066118 p.Asn25Ser missense_variant 0.25
Rv2752c 3066150 c.42C>A synonymous_variant 0.29
Rv2752c 3066153 p.Ser13Thr missense_variant 0.29
Rv2752c 3066158 p.Thr12Ala missense_variant 0.33
Rv2752c 3066161 c.31C>T synonymous_variant 0.33
Rv2752c 3066162 c.30C>G synonymous_variant 0.33
Rv2752c 3066165 c.27T>C synonymous_variant 0.33
Rv2752c 3066176 p.Pro6Ala missense_variant 0.33
Rv2752c 3066177 c.15T>C synonymous_variant 0.33
Rv2752c 3066270 c.-79G>A upstream_gene_variant 0.2
Rv2752c 3066276 c.-85G>A upstream_gene_variant 0.22
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.2
Rv2752c 3066290 c.-99G>A upstream_gene_variant 0.17
Rv2752c 3066291 c.-100G>A upstream_gene_variant 0.17
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.2
Rv2752c 3066315 c.-124C>T upstream_gene_variant 0.22
thyX 3067515 p.Ser144Thr missense_variant 0.22
thyX 3067530 p.Ala139Ser missense_variant 0.29
thyX 3067545 p.Glu134Ala missense_variant 0.29
thyX 3067549 p.Thr133Ala missense_variant 0.29
thyX 3067556 p.His130Gln missense_variant 0.25
thyX 3067559 c.387C>G synonymous_variant 0.25
thyX 3067565 p.Asp127Glu missense_variant 0.25
thyX 3067570 p.Ala126Pro missense_variant 0.33
thyX 3067685 c.261A>C synonymous_variant 0.22
thyX 3067691 p.Ile85Leu missense_variant 0.22
thyX 3067694 c.252G>C synonymous_variant 0.22
thyX 3067718 c.228C>G synonymous_variant 1.0
thyX 3067721 c.225T>C synonymous_variant 1.0
thyX 3067727 c.219A>C synonymous_variant 0.33
thyX 3067736 p.Phe70Leu missense_variant 0.33
thyX 3067739 c.207T>C synonymous_variant 0.33
thyX 3067761 p.Arg62Lys missense_variant 0.29
thyX 3067765 p.Leu61Ile missense_variant 0.29
thyX 3067772 c.174C>G synonymous_variant 0.29
thyX 3067781 c.165C>A synonymous_variant 0.29
thyX 3067793 c.153T>C synonymous_variant 0.29
thyX 3067799 c.147G>A synonymous_variant 0.25
thyX 3067802 c.144C>G synonymous_variant 0.25
thyX 3067814 c.132T>C synonymous_variant 0.33
thyX 3067850 c.96A>C synonymous_variant 0.83
thyX 3067869 p.Thr26Ser missense_variant 0.8
thyX 3067874 c.72C>G synonymous_variant 0.75
thyX 3067883 c.63C>G synonymous_variant 0.6
thyX 3067886 c.60A>C synonymous_variant 0.6
thyX 3067889 c.57C>G synonymous_variant 0.6
thyX 3067898 p.Asp16Glu missense_variant 0.6
thyX 3067935 p.Thr4Ile missense_variant 0.33
thyA 3073892 c.580T>C synonymous_variant 1.0
thyA 3073898 p.Ala192Ser missense_variant 1.0
thyA 3073917 c.555C>G synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087272 c.453A>C synonymous_variant 0.5
ald 3087278 p.Gln153His missense_variant 0.57
ald 3087281 c.462G>C synonymous_variant 0.67
ald 3087284 c.465C>G synonymous_variant 0.57
ald 3087290 c.471T>C synonymous_variant 0.57
ald 3087305 c.486G>C synonymous_variant 0.57
ald 3087311 c.492C>G synonymous_variant 0.57
ald 3087318 p.Glu167Lys missense_variant 0.57
ald 3087344 c.525C>G synonymous_variant 0.67
ald 3087347 c.528C>G synonymous_variant 0.57
ald 3087356 c.537C>G synonymous_variant 0.57
ald 3087704 c.885T>C synonymous_variant 0.33
ald 3087716 c.897G>C synonymous_variant 0.4
ald 3087726 p.Ala303Ser missense_variant 0.4
ald 3087729 p.Ser304Ala missense_variant 0.4
ald 3087737 c.918G>C synonymous_variant 0.5
ald 3087749 c.930C>G synonymous_variant 0.4
ald 3087750 p.Tyr311Val missense_variant 0.4
ald 3087761 c.942C>G synonymous_variant 0.29
ald 3087770 c.951G>C synonymous_variant 0.29
Rv3083 3448759 p.Ala86Thr missense_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612988 c.128delT frameshift_variant 0.25
Rv3236c 3613073 p.Leu15Ser missense_variant 0.25
fbiA 3640347 c.-196A>G upstream_gene_variant 0.2
fbiA 3640349 c.-194A>G upstream_gene_variant 0.2
fbiA 3640350 c.-193C>T upstream_gene_variant 0.2
fbiA 3640365 c.-178C>G upstream_gene_variant 0.25
fbiB 3640857 c.-678G>C upstream_gene_variant 0.4
fbiB 3640866 c.-669T>C upstream_gene_variant 0.4
fbiA 3640871 p.Ala110Gly missense_variant 0.4
fbiB 3640878 c.-657T>C upstream_gene_variant 0.5
fbiB 3640899 c.-636G>C upstream_gene_variant 0.4
fbiA 3640900 p.Gln120Asn missense_variant 0.4
fbiB 3640914 c.-621C>G upstream_gene_variant 0.4
fbiA 3640930 p.Glu130Lys missense_variant 0.22
fbiA 3641447 p.Thr302Met missense_variant 1.0
alr 3840995 p.Leu142Phe missense_variant 0.29
alr 3841059 p.Gly121Ala missense_variant 0.25
alr 3841304 p.Met39Ile missense_variant 0.22
rpoA 3877553 p.Glu319Lys missense_variant 1.0
rpoA 3877668 c.840A>G synonymous_variant 0.33
rpoA 3877679 p.Ala277Ser missense_variant 0.6
rpoA 3877686 c.822A>G synonymous_variant 0.6
rpoA 3877692 c.816G>C synonymous_variant 0.75
rpoA 3877704 c.804G>C synonymous_variant 0.67
rpoA 3877743 c.765T>C synonymous_variant 0.4
rpoA 3878103 c.405A>G synonymous_variant 0.33
rpoA 3878172 c.336G>C synonymous_variant 0.4
rpoA 3878187 c.321C>G synonymous_variant 0.43
rpoA 3878193 c.315T>C synonymous_variant 0.43
rpoA 3878199 c.309T>C synonymous_variant 0.43
rpoA 3878217 c.291A>G synonymous_variant 0.5
rpoA 3878226 c.282C>G synonymous_variant 0.43
rpoA 3878232 c.276G>C synonymous_variant 0.43
rpoA 3878247 c.261G>C synonymous_variant 0.38
rpoA 3878271 c.237T>C synonymous_variant 0.25
rpoA 3878284 p.Glu75Ala missense_variant 0.2
rpoA 3878424 c.84G>C synonymous_variant 0.67
rpoA 3878436 c.72A>G synonymous_variant 0.67
rpoA 3878442 c.66G>C synonymous_variant 0.67
rpoA 3878454 c.54A>C synonymous_variant 0.67
rpoA 3878472 p.Asp12Glu missense_variant 1.0
rpoA 3878478 c.30C>G synonymous_variant 1.0
rpoA 3878484 c.24C>A synonymous_variant 1.0
rpoA 3878490 c.18C>A synonymous_variant 1.0
rpoA 3878496 c.12A>T synonymous_variant 1.0
clpC1 4038212 c.2493T>C synonymous_variant 0.4
clpC1 4038239 c.2466T>C synonymous_variant 0.4
clpC1 4038255 p.Val817Lys missense_variant 0.5
clpC1 4038271 p.Pro812Ala missense_variant 1.0
clpC1 4038272 p.Gly811Ser missense_variant 1.0
clpC1 4038275 c.2430A>G synonymous_variant 1.0
clpC1 4038278 c.2427T>C synonymous_variant 1.0
clpC1 4038293 c.2412G>C synonymous_variant 0.75
clpC1 4038302 c.2403C>G synonymous_variant 0.75
clpC1 4038308 c.2397G>T synonymous_variant 0.5
clpC1 4038860 c.1845G>C synonymous_variant 0.4
clpC1 4038878 c.1827A>G synonymous_variant 0.29
clpC1 4038908 c.1797C>G synonymous_variant 0.5
clpC1 4038914 c.1791G>C synonymous_variant 0.5
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.5
clpC1 4039022 c.1683A>G synonymous_variant 0.3
clpC1 4039064 c.1641C>T synonymous_variant 0.58
clpC1 4039097 c.1608G>C synonymous_variant 0.78
clpC1 4039103 c.1602T>C synonymous_variant 0.7
clpC1 4039106 c.1599G>C synonymous_variant 0.7
clpC1 4039112 c.1593C>G synonymous_variant 0.67
clpC1 4039121 c.1584T>C synonymous_variant 0.75
clpC1 4039142 c.1563A>G synonymous_variant 0.67
clpC1 4039145 c.1560G>C synonymous_variant 0.67
clpC1 4039169 p.Glu512Asp missense_variant 0.67
clpC1 4039172 c.1533A>G synonymous_variant 0.67
clpC1 4039178 c.1527G>C synonymous_variant 0.67
clpC1 4039183 c.1522T>C synonymous_variant 0.67
clpC1 4039226 c.1479T>C synonymous_variant 0.5
clpC1 4039430 c.1275T>C synonymous_variant 0.6
clpC1 4039442 c.1263A>G synonymous_variant 0.67
clpC1 4039454 c.1251A>G synonymous_variant 1.0
clpC1 4039463 c.1242C>G synonymous_variant 1.0
clpC1 4039466 c.1239T>C synonymous_variant 1.0
clpC1 4039469 c.1236T>C synonymous_variant 1.0
clpC1 4039480 c.1225C>A synonymous_variant 1.0
clpC1 4039481 c.1224T>G synonymous_variant 1.0
clpC1 4039517 c.1188C>G synonymous_variant 0.86
clpC1 4039556 c.1149G>C synonymous_variant 0.5
clpC1 4039559 c.1146C>G synonymous_variant 0.5
clpC1 4039562 c.1143C>G synonymous_variant 0.5
clpC1 4039565 c.1140G>C synonymous_variant 0.5
clpC1 4039570 p.Met379Leu missense_variant 0.5
clpC1 4039576 p.Ala377Pro missense_variant 0.6
clpC1 4039577 c.1128T>C synonymous_variant 0.6
clpC1 4039589 c.1116G>C synonymous_variant 0.6
clpC1 4039610 c.1095G>C synonymous_variant 0.6
clpC1 4039661 c.1044T>G synonymous_variant 0.5
clpC1 4039664 c.1041G>C synonymous_variant 0.5
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.29
clpC1 4039931 c.774T>C synonymous_variant 0.29
clpC1 4039937 c.768G>C synonymous_variant 0.33
clpC1 4039946 c.759A>C synonymous_variant 0.75
clpC1 4039952 c.753T>C synonymous_variant 0.75
clpC1 4039979 c.726C>G synonymous_variant 1.0
clpC1 4039988 c.717C>G synonymous_variant 1.0
clpC1 4039991 c.714G>C synonymous_variant 1.0
clpC1 4040021 c.684A>C synonymous_variant 0.75
clpC1 4040024 c.681A>G synonymous_variant 0.75
clpC1 4040033 c.672G>C synonymous_variant 0.75
clpC1 4040036 c.669C>G synonymous_variant 0.75
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.67
clpC1 4040093 c.612C>G synonymous_variant 0.67
clpC1 4040105 c.600C>G synonymous_variant 0.8
clpC1 4040147 c.558A>G synonymous_variant 0.8
clpC1 4040162 c.543G>C synonymous_variant 0.5
clpC1 4040165 c.540G>C synonymous_variant 0.5
clpC1 4040171 c.534C>G synonymous_variant 0.57
embC 4240867 c.1005T>C synonymous_variant 0.18
embC 4240870 c.1008T>C synonymous_variant 0.18
embC 4240873 c.1011C>G synonymous_variant 0.18
embC 4240879 c.1017G>C synonymous_variant 0.2
embC 4240880 p.Ala340Thr missense_variant 0.18
embC 4240885 c.1023T>C synonymous_variant 0.17
embC 4240897 c.1035C>G synonymous_variant 1.0
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.18
embC 4240903 c.1041C>G synonymous_variant 0.18
embC 4240911 p.Ala350Val missense_variant 0.2
embC 4240921 c.1059C>G synonymous_variant 0.25
embC 4240924 c.1062C>G synonymous_variant 0.2
embC 4240936 c.1074A>G synonymous_variant 0.18
embC 4241449 c.1587C>G synonymous_variant 0.43
embC 4241453 p.Ile531Val missense_variant 0.43
embC 4241479 c.1617C>G synonymous_variant 0.44
embC 4241480 c.1618T>C synonymous_variant 0.57
embC 4241488 c.1626G>C synonymous_variant 0.5
embC 4241496 p.Ala545Gly missense_variant 0.5
embC 4241500 c.1638A>C synonymous_variant 0.5
embC 4241501 p.Ser547Thr missense_variant 0.5
embC 4241506 c.1644G>C synonymous_variant 0.4
embC 4241518 c.1656A>G synonymous_variant 0.4
embC 4241521 c.1659T>C synonymous_variant 0.33
embC 4241530 c.1668C>A synonymous_variant 0.33
embC 4241536 c.1674A>G synonymous_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242764 p.Val968Leu missense_variant 0.15
embC 4242779 p.Asn973Asp missense_variant 0.15
embC 4242791 p.Ala977Ser missense_variant 0.15
embA 4242796 c.-437G>C upstream_gene_variant 0.15
embA 4242799 c.-434T>C upstream_gene_variant 0.15
embC 4242803 p.Val981Leu missense_variant 0.85
embA 4245009 p.Ala593Ser missense_variant 0.2
embA 4245053 c.1821G>C synonymous_variant 0.25
embA 4245060 c.1828T>C synonymous_variant 0.4
embA 4245083 c.1851A>C synonymous_variant 0.67
embA 4245089 c.1857G>C synonymous_variant 1.0
embA 4245092 c.1860C>G synonymous_variant 1.0
embA 4245101 c.1869G>C synonymous_variant 1.0
embA 4245137 c.1905T>C synonymous_variant 0.67
embA 4245146 c.1914G>A synonymous_variant 0.67
embA 4245149 c.1917C>G synonymous_variant 0.67
embA 4245153 p.Ile641Val missense_variant 0.67
embA 4245182 c.1950T>C synonymous_variant 0.67
embA 4245189 c.1957C>T synonymous_variant 0.4
embA 4245198 p.Leu656Ile missense_variant 0.4
embA 4245323 p.Met697Ile missense_variant 0.5
embA 4245885 p.Asp885Thr missense_variant 0.75
embA 4245892 p.Ile887Thr missense_variant 0.75
embB 4245905 c.-609C>G upstream_gene_variant 0.6
embA 4245927 p.Thr899Ala missense_variant 0.33
embA 4245930 p.Gly900Arg missense_variant 0.5
embA 4246264 p.His1011Arg missense_variant 0.33
embB 4246292 c.-222A>G upstream_gene_variant 0.33
embA 4246305 p.Ser1025Glu missense_variant 0.4
embA 4246308 p.Thr1026Ala missense_variant 0.4
embB 4246316 c.-198T>G upstream_gene_variant 0.4
embB 4246319 c.-195G>C upstream_gene_variant 0.4
embB 4248304 c.1791G>C synonymous_variant 0.67
embB 4248319 c.1806A>G synonymous_variant 0.5
embB 4248343 c.1830G>C synonymous_variant 0.67
embB 4248373 c.1860C>G synonymous_variant 0.33
embB 4248386 c.1873C>A synonymous_variant 0.33
embB 4248407 p.Leu632Val missense_variant 0.22
embB 4248410 p.Phe633Leu missense_variant 0.22
embB 4248419 p.Leu636Met missense_variant 0.33
embB 4248425 c.1912T>C synonymous_variant 0.33
embB 4248430 c.1917T>C synonymous_variant 0.33
embB 4248432 p.Trp640Phe missense_variant 0.33
embB 4248457 c.1944T>C synonymous_variant 0.43
embB 4249095 p.Ala861Val missense_variant 0.5
embB 4249408 c.2895G>A synonymous_variant 1.0
aftB 4267503 p.Thr445Asn missense_variant 0.33
aftB 4267518 p.Thr440Lys missense_variant 0.29
aftB 4268112 p.Ala242Asp missense_variant 0.33
aftB 4268144 c.693T>C synonymous_variant 0.29
ubiA 4269220 p.Ala205Lys missense_variant 0.75
aftB 4269222 c.-386T>C upstream_gene_variant 0.75
aftB 4269234 c.-398A>G upstream_gene_variant 0.75
aftB 4269242 c.-406C>T upstream_gene_variant 0.75
ubiA 4269243 p.His197Gln missense_variant 0.75
aftB 4269249 c.-413G>A upstream_gene_variant 0.75
aftB 4269258 c.-422C>T upstream_gene_variant 1.0
ubiA 4269475 p.Leu120Gln missense_variant 0.2
ubiA 4269906 c.-73G>C upstream_gene_variant 0.25
ethA 4328449 c.-976C>G upstream_gene_variant 0.25
ethA 4328463 c.-990G>C upstream_gene_variant 0.2
ethA 4328467 c.-994G>T upstream_gene_variant 0.2
ethA 4328470 c.-998_-997delAGinsGC upstream_gene_variant 0.17
whiB6 4338498 p.Glu8Asp missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407905 p.Phe100Ile missense_variant 0.5