TB-Profiler result

Run: ERR4819370

Summary

Run ID: ERR4819370

Sample name:

Date: 01-04-2023 16:04:22

Number of reads: 1692972

Percentage reads mapped: 99.96

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.11
rrl 1474161 n.504A>G non_coding_transcript_exon_variant 0.14
rrl 1474792 n.1135C>G non_coding_transcript_exon_variant 0.22
PPE35 2170048 p.Leu189Val missense_variant 0.26
PPE35 2170053 p.Thr187Ser missense_variant 0.26
PPE35 2170066 p.Ala183Thr missense_variant 0.11