TB-Profiler result

Run: ERR4819395

Summary

Run ID: ERR4819395

Sample name:

Date: 01-04-2023 16:05:09

Number of reads: 1147970

Percentage reads mapped: 99.78

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576750 p.Lys468Thr missense_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.15
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.15
kasA 2518061 c.-54G>A upstream_gene_variant 0.12
fbiD 3339741 c.624G>T synonymous_variant 0.15
fbiD 3339744 c.627A>C synonymous_variant 0.15
clpC1 4038169 c.2531_2535delAGCCG frameshift_variant 0.15
clpC1 4038178 c.2526_2527insT frameshift_variant 0.12
clpC1 4038183 p.Gly841Ala missense_variant 0.1
embB 4247545 p.Ser344Arg missense_variant 0.1
aftB 4267644 p.Asp398Gly missense_variant 0.12