TB-Profiler result

Run: ERR4819575
Summary

Run ID: ERR4819575

Sample name:

Date: 01-04-2023 16:11:10

Number of reads: 210724

Percentage reads mapped: 81.41

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
mshA 575934 p.Pro196Leu missense_variant 0.2
mshA 576470 c.1125_1126delCG frameshift_variant 0.29
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406087 c.1254T>C synonymous_variant 0.4
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 1.0
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.67
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.67
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.5
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.5
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.67
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 1.0
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 1.0
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.75
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.75
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 1.0
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.8
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.5
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.5
rpsA 1833685 c.144G>C synonymous_variant 0.33
rpsA 1833724 c.183C>T synonymous_variant 0.5
rpsA 1834302 p.Val254Gly missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726402 c.212_213dupTC frameshift_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448484 c.-20T>A upstream_gene_variant 0.18
Rv3083 3449437 p.Gly312Arg missense_variant 0.67
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
ddn 3986864 c.21G>A synonymous_variant 0.25
clpC1 4039979 c.726C>G synonymous_variant 0.67
clpC1 4039982 c.723G>A synonymous_variant 0.67
clpC1 4039991 c.714G>T synonymous_variant 0.67
clpC1 4039994 p.Glu237Asp missense_variant 0.67
clpC1 4040000 p.His235Lys missense_variant 0.5
clpC1 4040003 c.702G>C synonymous_variant 0.5
clpC1 4040009 c.696C>G synonymous_variant 0.75
clpC1 4040015 c.690G>C synonymous_variant 0.75
clpC1 4040021 c.684A>C synonymous_variant 0.6
clpC1 4040024 c.681A>G synonymous_variant 0.6
clpC1 4040033 c.672G>C synonymous_variant 0.5
embC 4241003 p.Ala381Thr missense_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243493 c.261C>T synonymous_variant 0.18
embA 4244619 c.1387T>C synonymous_variant 0.33
aftB 4267624 p.Ser405Pro missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0