TB-Profiler result

Run: ERR4819740
Summary

Run ID: ERR4819740

Sample name:

Date: 01-04-2023 16:16:39

Number of reads: 1577

Percentage reads mapped: 19.7

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8816 c.1515C>G synonymous_variant 1.0
gyrA 8818 p.Ser506Asn missense_variant 1.0
gyrA 8828 c.1527T>C synonymous_variant 1.0
gyrA 8829 c.1528T>C synonymous_variant 1.0
gyrA 8852 c.1551T>C synonymous_variant 1.0
gyrA 8867 c.1566A>G synonymous_variant 1.0
gyrA 8870 c.1569G>C synonymous_variant 1.0
gyrA 8873 c.1572A>C synonymous_variant 1.0
gyrA 8891 c.1590G>A synonymous_variant 1.0
rplC 800612 c.-197A>G upstream_gene_variant 1.0
rplC 800618 c.-191T>C upstream_gene_variant 1.0
rplC 800627 c.-182C>T upstream_gene_variant 1.0
rplC 800648 c.-161A>T upstream_gene_variant 1.0
rplC 800654 c.-155T>C upstream_gene_variant 1.0
rplC 800720 c.-89T>C upstream_gene_variant 1.0
rpsA 1834765 p.Glu408Asp missense_variant 1.0
rpsA 1834775 p.Ala412Thr missense_variant 1.0
rpsA 1834780 c.1239A>G synonymous_variant 1.0
rpsA 1834786 c.1245A>G synonymous_variant 1.0
rpsA 1834789 c.1248T>C synonymous_variant 1.0
rpsA 1834792 c.1251G>C synonymous_variant 1.0
Rv2752c 3066018 c.174T>C synonymous_variant 1.0
Rv2752c 3066024 c.168T>G synonymous_variant 1.0
Rv2752c 3066040 p.Gly51Thr missense_variant 1.0
Rv2752c 3066042 c.150T>C synonymous_variant 1.0
Rv2752c 3066045 c.147T>C synonymous_variant 1.0
Rv2752c 3066050 p.Leu48Met missense_variant 1.0
Rv2752c 3066054 c.138T>G synonymous_variant 1.0
Rv2752c 3066066 c.126T>C synonymous_variant 1.0
Rv2752c 3066074 c.118C>T synonymous_variant 1.0
Rv2752c 3066075 c.117A>G synonymous_variant 1.0
Rv2752c 3066078 c.114C>T synonymous_variant 1.0
Rv2752c 3066102 c.90C>T synonymous_variant 1.0
clpC1 4039850 c.855T>C synonymous_variant 1.0
embB 4249417 c.2904A>G synonymous_variant 1.0
embB 4249423 p.Asp970Glu missense_variant 1.0
embB 4249424 p.Leu971Met missense_variant 1.0
embB 4249429 c.2916C>T synonymous_variant 1.0
embB 4249432 c.2919A>G synonymous_variant 1.0
embB 4249441 c.2928A>G synonymous_variant 1.0
embB 4249444 c.2931T>C synonymous_variant 1.0
embB 4249469 p.Leu986Met missense_variant 1.0
embB 4249486 c.2973T>G synonymous_variant 1.0
embB 4249498 c.2985G>C synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0