TB-Profiler result

Run: ERR4819797

Summary

Run ID: ERR4819797

Sample name:

Date: 01-04-2023 16:18:33

Number of reads: 96515

Percentage reads mapped: 99.04

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7246 c.-56T>C upstream_gene_variant 0.67
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoC 764584 c.1215G>A synonymous_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303531 p.Met201Val missense_variant 0.33
fbiC 1305350 p.Leu807Pro missense_variant 0.4
atpE 1461235 p.Tyr64Phe missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834850 p.Ala437Ser missense_variant 0.4
tlyA 1918559 p.Ser207Leu missense_variant 0.67
PPE35 2169543 p.Gly357Val missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
folC 2747727 c.-129C>G upstream_gene_variant 0.67
ribD 2986710 c.-129C>T upstream_gene_variant 1.0
Rv2752c 3065824 p.Pro123Leu missense_variant 1.0
thyX 3067956 c.-11A>T upstream_gene_variant 0.67
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449643 p.Asn380Lys missense_variant 1.0
fprA 3474707 p.Thr234Ile missense_variant 1.0
fbiA 3640452 c.-91C>A upstream_gene_variant 0.4
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4243002 p.Ser1047Ile missense_variant 0.22
ethR 4326808 c.-741G>A upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0