TB-Profiler result

Run: ERR4820093

Summary

Run ID: ERR4820093

Sample name:

Date: 01-04-2023 16:28:46

Number of reads: 62540

Percentage reads mapped: 98.3

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.95
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
fbiC 1303146 c.216G>A synonymous_variant 0.67
rpsA 1834561 c.1020C>T synonymous_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
eis 2715466 c.-134C>T upstream_gene_variant 0.5
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
folC 2747245 c.354G>A synonymous_variant 0.67
Rv2752c 3065008 p.Pro395Leu missense_variant 0.67
ddn 3987086 c.243C>A synonymous_variant 0.5
panD 4044023 c.259C>T synonymous_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
ethA 4328257 c.-784A>G upstream_gene_variant 0.67
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0