TB-Profiler result

Run: ERR4820142
Summary

Run ID: ERR4820142

Sample name:

Date: 01-04-2023 16:30:32

Number of reads: 57191

Percentage reads mapped: 90.02

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 575907 p.Ala187Val missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 0.67
rpoC 764230 p.Gln287His missense_variant 1.0
rpoC 765014 p.Ala549Ser missense_variant 0.5
mmpL5 777329 c.1152C>T synonymous_variant 0.67
mmpL5 778327 p.Gln52* stop_gained 0.5
mmpL5 779010 c.-530G>A upstream_gene_variant 0.5
fbiC 1304000 p.Val357Ala missense_variant 0.67
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1918018 p.Ile27Phe missense_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2168270 c.2343G>T synonymous_variant 0.5
Rv1979c 2222969 p.Ala66Thr missense_variant 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746870 p.Glu243Asp missense_variant 1.0
thyX 3067817 c.129C>T synonymous_variant 1.0
Rv3236c 3612423 p.Val232Met missense_variant 1.0
whiB6 4338567 c.-46C>A upstream_gene_variant 1.0
whiB6 4338594 c.-73T>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0