TB-Profiler result

Run: ERR4820170

Summary

Run ID: ERR4820170

Sample name:

Date: 01-04-2023 16:31:29

Number of reads: 113417

Percentage reads mapped: 98.99

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6093 p.His285Arg missense_variant 0.5
gyrA 7585 p.Ser95Thr missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 761861 c.2055C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778889 p.Lys6Arg missense_variant 0.25
rpsL 781363 c.-197T>G upstream_gene_variant 0.33
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833418 c.-124T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168493 p.Gly707Asp missense_variant 0.22
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3613292 c.-177dupG upstream_gene_variant 0.67
ddn 3987236 c.393A>G synonymous_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249403 p.Thr964Pro missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0