TB-Profiler result

Run: ERR4820216
Summary

Run ID: ERR4820216

Sample name:

Date: 01-04-2023 16:33:13

Number of reads: 1231159

Percentage reads mapped: 99.37

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8147 p.Asn282Lys missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620500 p.Gly204Ser missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 779307 c.-827T>C upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474438 n.781A>G non_coding_transcript_exon_variant 0.1
inhA 1674865 p.Trp222Arg missense_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155656 p.Lys152Asn missense_variant 0.12
Rv1979c 2222130 c.1035A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519062 c.948T>G synonymous_variant 0.11
kasA 2519065 c.951C>A synonymous_variant 0.11
folC 2747582 p.Ser6Cys missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339276 c.159C>T synonymous_variant 0.12
Rv3083 3448633 p.Thr44Ala missense_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612015 p.Ile368Leu missense_variant 0.11
Rv3236c 3612541 c.576G>A synonymous_variant 0.12
fbiA 3641241 p.Leu233Phe missense_variant 0.12
fbiB 3642340 p.Asp269Val missense_variant 0.11
rpoA 3878692 c.-185C>T upstream_gene_variant 0.12
clpC1 4038260 p.Asp815Glu missense_variant 0.12
embC 4242164 p.Pro768Thr missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4244756 p.Glu508Asp missense_variant 0.12
embA 4245973 p.Ile914Asn missense_variant 0.15
embB 4249408 c.2895G>A synonymous_variant 1.0
aftB 4267958 c.879G>T synonymous_variant 0.29
aftB 4269696 c.-860C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0