TB-Profiler result

Run: ERR4820464
Summary

Run ID: ERR4820464

Sample name:

Date: 01-04-2023 16:41:45

Number of reads: 16076

Percentage reads mapped: 64.13

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6774 p.Gly512Glu missense_variant 1.0
rpoC 763605 p.Gly79Val missense_variant 1.0
rplC 800725 c.-84C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.5
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.5
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 1.0
rrs 1472261 n.416G>T non_coding_transcript_exon_variant 0.5
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.67
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 1.0
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
embC 4242753 p.Arg964Leu missense_variant 0.5