TB-Profiler result

Run: ERR4820643

Summary

Run ID: ERR4820643

Sample name:

Date: 01-04-2023 16:47:40

Number of reads: 1162370

Percentage reads mapped: 99.96

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 619911 c.21C>T synonymous_variant 0.11
ccsA 620748 c.858T>G synonymous_variant 0.24
rpoB 759620 c.-187A>C upstream_gene_variant 0.2
Rv1258c 1407082 p.Ala87Ser missense_variant 0.12
Rv1258c 1407161 c.180G>A synonymous_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473665 n.8T>A non_coding_transcript_exon_variant 0.13
rrl 1474241 n.584G>A non_coding_transcript_exon_variant 0.33
thyA 3074592 c.-122delC upstream_gene_variant 0.14
Rv3083 3448767 c.264C>A synonymous_variant 0.15
clpC1 4038309 p.Val799Ala missense_variant 0.1
embC 4242211 c.2349A>G synonymous_variant 0.12