TB-Profiler result

Run: ERR4820944
Summary

Run ID: ERR4820944

Sample name:

Date: 01-04-2023 16:58:58

Number of reads: 8150588

Percentage reads mapped: 98.65

Strain: lineage4.1.1.3

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.53 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5248 c.9C>T synonymous_variant 1.0
gyrB 5805 p.Thr189Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.1
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.55
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.64
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.64
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.7
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.7
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.71
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.71
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.69
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.72
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.62
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.57
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.42
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.82
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.69
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.69
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.52
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.22
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.36
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.48
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.52
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.58
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.61
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.61
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.59
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.53
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.46
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.25
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.25
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.12
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.11
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.18
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.22
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.17
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.12
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.18
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.12
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.14
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.15
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.12
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.13
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.19
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.19
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.67
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.67
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.4
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.4
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.33
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.33
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.29
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.29
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.25
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.25
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.25
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.25
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.25
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.29
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.5
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.25
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.25
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.25
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.25
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.29
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.25
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.15
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0