TB-Profiler result

Run: ERR4820947
Summary

Run ID: ERR4820947

Sample name:

Date: 01-04-2023 16:58:28

Number of reads: 163428

Percentage reads mapped: 99.24

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490863 c.81C>A synonymous_variant 0.22
fgd1 490869 c.87C>T synonymous_variant 0.22
fgd1 490890 c.108C>G synonymous_variant 0.17
fgd1 490896 c.114C>T synonymous_variant 0.17
mshA 575357 p.Val4Met missense_variant 1.0
rpoB 760384 p.Leu193Pro missense_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776526 p.Met652Thr missense_variant 0.29
mmpL5 777731 c.750C>G synonymous_variant 0.67
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303307 p.Asp126Gly missense_variant 0.5
fbiC 1304159 p.Val410Gly missense_variant 0.4
fbiC 1304925 c.1995G>A synonymous_variant 1.0
Rv1258c 1406700 p.Glu214Gly missense_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 1.0
fabG1 1673684 p.Val82Asp missense_variant 0.33
rpsA 1834118 p.Gln193* stop_gained 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102852 p.Ser64Tyr missense_variant 0.22
katG 2156521 c.-410C>A upstream_gene_variant 0.25
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747265 p.Gly112Ser missense_variant 0.67
ald 3086997 p.Thr60Gly missense_variant 0.4
fprA 3474368 p.Gly121Asp missense_variant 1.0
fbiA 3640443 c.-100A>G upstream_gene_variant 0.5
rpoA 3878142 c.366C>T synonymous_variant 0.33
clpC1 4039645 p.His354Asp missense_variant 1.0
embC 4242749 p.Pro963Thr missense_variant 0.22
embC 4243104 p.Thr1081Asn missense_variant 0.67
embA 4243159 c.-74C>A upstream_gene_variant 0.4
embB 4249562 p.Asp1017Tyr missense_variant 0.25
aftB 4267010 c.1827A>G synonymous_variant 0.33
ubiA 4269238 p.Ala199Val missense_variant 0.4
whiB6 4338198 p.Asp108Glu missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338705 c.-184A>T upstream_gene_variant 0.29
gid 4408370 c.-168G>C upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0