TB-Profiler result

Run: ERR4821038
Summary

Run ID: ERR4821038

Sample name:

Date: 01-04-2023 17:01:35

Number of reads: 33185

Percentage reads mapped: 95.09

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 575907 p.Ala187Val missense_variant 1.0
rpoC 764631 p.Arg421His missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 1.0
ndh 2103225 c.-183A>C upstream_gene_variant 0.5
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223014 p.Tyr51Asn missense_variant 1.0
Rv2752c 3065704 p.Gly163Glu missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
Rv3236c 3613055 p.Leu21Pro missense_variant 1.0
rpoA 3878393 p.Arg39Cys missense_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4248115 c.1602C>T synonymous_variant 1.0
aftB 4267080 p.Arg586Gln missense_variant 1.0
aftB 4268738 c.99C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408007 p.Val66Leu missense_variant 1.0