TB-Profiler result

Run: ERR4821978
Summary

Run ID: ERR4821978

Sample name:

Date: 01-04-2023 17:33:54

Number of reads: 188520

Percentage reads mapped: 97.7

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9569 c.2268C>T synonymous_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575423 p.Arg26Cys missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 759615 c.-192A>C upstream_gene_variant 0.33
rpoB 759620 c.-187A>C upstream_gene_variant 0.33
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 764497 c.1128A>G synonymous_variant 0.33
rpoC 764503 c.1134G>C synonymous_variant 0.4
rpoC 764521 c.1152T>C synonymous_variant 0.33
rpoC 764536 c.1167G>C synonymous_variant 0.33
rpoC 764539 c.1170C>G synonymous_variant 0.33
rpoC 765070 c.1701G>A synonymous_variant 0.2
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.38
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833504 c.-38T>A upstream_gene_variant 0.17
rpsA 1834880 p.Asp447Asn missense_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169278 c.1335T>C synonymous_variant 1.0
PPE35 2169281 c.1332T>G synonymous_variant 1.0
PPE35 2169287 c.1326T>C synonymous_variant 1.0
PPE35 2169865 p.Ala250Thr missense_variant 0.18
PPE35 2169902 p.Leu237Phe missense_variant 0.17
PPE35 2169910 p.Asn235Tyr missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859454 p.Val322Gly missense_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3841133 c.288G>A synonymous_variant 0.5
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
aftB 4266971 c.1866C>A synonymous_variant 0.33
ubiA 4269116 p.Arg240Ser missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0