TB-Profiler result

Run: ERR4822209

Summary

Run ID: ERR4822209

Sample name:

Date: 01-04-2023 17:41:59

Number of reads: 1005751

Percentage reads mapped: 99.95

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8064 p.Gly255Arg missense_variant 0.1
rpoB 761152 p.Leu449Gln missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.12
rrs 1472480 n.635G>A non_coding_transcript_exon_variant 0.2
rrl 1476133 n.2476G>A non_coding_transcript_exon_variant 0.25
rrl 1476438 n.2781G>A non_coding_transcript_exon_variant 0.1
PPE35 2167667 c.2946C>T synonymous_variant 0.1
Rv2752c 3065453 p.Gln247Lys missense_variant 0.11
Rv3083 3449021 p.Leu173His missense_variant 0.18
fprA 3474196 p.Ser64Gly missense_variant 0.11
Rv3236c 3612879 p.Thr80Ser missense_variant 0.17
embB 4249584 p.Asp1024Val missense_variant 0.1
embB 4249655 p.Val1048Phe missense_variant 0.15