TB-Profiler result

Run: ERR4872168
Summary

Run ID: ERR4872168

Sample name:

Date: 01-04-2023 21:25:01

Number of reads: 15490

Percentage reads mapped: 98.47

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
mshA 575418 p.Ala24Val missense_variant 1.0
mmpL5 777935 c.546C>A synonymous_variant 1.0
inhA 1674220 p.Gly7Cys missense_variant 1.0
inhA 1674705 p.Leu168Phe missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
alr 3840967 p.Ala152Ser missense_variant 0.5
clpC1 4039314 p.Arg464Leu missense_variant 1.0