TB-Profiler result

Run: ERR495005
Summary

Run ID: ERR495005

Sample name:

Date: 01-04-2023 21:34:25

Number of reads: 89815

Percentage reads mapped: 98.21

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.98
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5681 p.Gln148* stop_gained 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoC 764531 p.Gly388Cys missense_variant 1.0
rpsA 1833422 c.-120G>A upstream_gene_variant 1.0
rpsA 1834657 c.1116G>A synonymous_variant 1.0
rpsA 1834691 p.Tyr384Asn missense_variant 0.67
PPE35 2168549 p.Asn688Lys missense_variant 0.67
fprA 3474446 p.Gly147Val missense_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
fbiA 3640891 p.Gln117Lys missense_variant 1.0
fbiA 3640900 p.Gln120Lys missense_variant 1.0
clpC1 4039363 p.Ala448Thr missense_variant 1.0
embC 4241972 p.Val704Ile missense_variant 1.0
embC 4242124 c.2262C>T synonymous_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4249691 p.Asp1060Asn missense_variant 1.0
embB 4249761 p.Ala1083Val missense_variant 0.4