TB-Profiler result

Run: ERR495086
Summary

Run ID: ERR495086

Sample name:

Date: 01-04-2023 21:37:37

Number of reads: 61367

Percentage reads mapped: 99.4

Strain: lineage4.9;lineage4.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.09
lineage4.9 Euro-American (H37Rv-like) T1 None 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6650 p.Arg471Ser missense_variant 0.67
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 766211 p.Glu948* stop_gained 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801045 c.237A>G synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.5
rpsA 1834836 p.Met432Thr missense_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
eis 2715267 c.66C>A synonymous_variant 0.67
folC 2746340 p.Ala420Val missense_variant 1.0
ribD 2987507 c.669G>T synonymous_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
embC 4241459 p.Arg533Ser missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267622 c.1215G>T synonymous_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0