TB-Profiler result

Run: ERR501640
Summary

Run ID: ERR501640

Sample name:

Date: 01-04-2023 21:48:19

Number of reads: 170069

Percentage reads mapped: 98.63

Strain: lineage4.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 0.09
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491594 p.Ala271Val missense_variant 0.29
rpoB 761581 p.Glu592Val missense_variant 0.4
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766389 p.Gly1007Asp missense_variant 0.67
rpsL 781928 c.369G>A synonymous_variant 1.0
Rv1258c 1406945 c.396C>A synonymous_variant 0.29
Rv1258c 1406959 p.Leu128Met missense_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473708 n.51G>A non_coding_transcript_exon_variant 0.22
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.67
rpsA 1834137 p.Arg199His missense_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170305 p.Ala103Glu missense_variant 0.5
PPE35 2170577 c.36G>A synonymous_variant 0.22
PPE35 2170666 c.-54G>A upstream_gene_variant 0.29
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747505 p.His32Asn missense_variant 0.5
folC 2747587 c.12G>A synonymous_variant 0.29
fbiD 3339273 c.156T>G synonymous_variant 0.25
fbiB 3641463 c.-72G>A upstream_gene_variant 0.4
fbiB 3641807 c.273C>G synonymous_variant 1.0
alr 3840789 p.Gln211Arg missense_variant 0.67
alr 3840802 p.Ile207Phe missense_variant 0.67
ddn 3986868 c.25C>T synonymous_variant 0.5
ddn 3986910 c.67C>A synonymous_variant 0.67
panD 4044420 c.-139G>A upstream_gene_variant 0.67
embC 4242803 p.Val981Leu missense_variant 1.0
embC 4242982 p.Met1040Ile missense_variant 0.33
embC 4243119 p.Trp1086Ser missense_variant 1.0
embA 4243746 p.Gly172Ser missense_variant 0.25
embA 4244816 c.1584G>A synonymous_variant 0.4
embB 4248604 c.2091G>A synonymous_variant 0.67
embB 4248763 c.2250C>A synonymous_variant 0.5
embB 4248790 c.2277C>A synonymous_variant 0.67
ethR 4327691 p.Asp48Gly missense_variant 1.0
ethR 4327732 p.Tyr62Asn missense_variant 0.33
ethA 4328294 c.-821C>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408363 c.-161G>A upstream_gene_variant 0.29