TB-Profiler result

Run: ERR501647
Summary

Run ID: ERR501647

Sample name:

Date: 2024-04-15T04:42:39.879862

Number of reads: 220207

Percentage reads mapped: 94.12

Median coverage: 4.0

Strain: lineage2.2.1.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.26
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.38
lineage2.2 East-Asian (Beijing) RD105;RD207 0.3
lineage2.2.1.1 East-Asian (Beijing) RD105;RD207;RD181;RD150 0.31
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
Rv1979c 2223014 p.Tyr51Asn missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
embB 4248115 c.1602C>T synonymous_variant 1.0 ethambutol Not assoc w R
gid 4407588 c.615A>G synonymous_variant 0.82 streptomycin Not assoc w R