TB-Profiler result

Run: ERR501647

Summary

Run ID: ERR501647

Sample name:

Date: 01-04-2023 21:48:32

Number of reads: 220207

Percentage reads mapped: 94.12

Strain:

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.67
gyrA 8690 c.1389C>T synonymous_variant 0.4
gyrA 9304 p.Gly668Asp missense_variant 0.88
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 0.67
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 766490 p.Arg1041Cys missense_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 0.86
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1461124 p.Gly27Asp missense_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473692 n.35G>A non_coding_transcript_exon_variant 0.18
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 0.67
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.5
fabG1 1673850 p.Phe137Leu missense_variant 0.67
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.67
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169396 p.Gly406Ala missense_variant 0.29
Rv1979c 2223014 p.Tyr51Asn missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289381 c.-140C>A upstream_gene_variant 0.29
pncA 2289384 c.-143C>A upstream_gene_variant 0.25
eis 2714846 p.Val163Ile missense_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.38
pepQ 2860462 c.-44C>A upstream_gene_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 0.8
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.86
fprA 3475156 p.Lys384* stop_gained 0.29
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
Rv3236c 3612981 p.Gly46Ser missense_variant 0.4
Rv3236c 3613129 c.-13A>T upstream_gene_variant 0.5
fbiB 3641157 c.-378C>T upstream_gene_variant 1.0
rpoA 3878020 p.Pro163Leu missense_variant 0.29
clpC1 4040809 c.-105G>T upstream_gene_variant 0.29
panD 4044109 p.Tyr58Phe missense_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4248115 c.1602C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
ubiA 4269040 p.Asp265Gly missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.82