TB-Profiler result

Run: ERR5162122
Summary

Run ID: ERR5162122

Sample name:

Date: 01-04-2023 22:28:27

Number of reads: 20331

Percentage reads mapped: 1.52

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155693 p.Ser140Asn missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 1.0
rrs 1472120 n.275G>C non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>T non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 1.0
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 1.0
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 1.0
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 1.0
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 1.0
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.67
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.89
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 1.0
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.89
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 1.0
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 1.0
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.8
rrl 1476483 n.2826G>A non_coding_transcript_exon_variant 0.8
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
katG 2155617 p.Ile165Met missense_variant 1.0
katG 2155626 c.486G>C synonymous_variant 1.0
katG 2155632 c.480A>G synonymous_variant 1.0
katG 2155637 p.Leu159Ile missense_variant 1.0
katG 2155655 p.Lys153Gln missense_variant 1.0
katG 2155661 p.Val151Ile missense_variant 1.0
katG 2155662 c.450G>C synonymous_variant 1.0
katG 2155670 c.442C>T synonymous_variant 1.0
katG 2155674 c.438G>C synonymous_variant 1.0
katG 2155680 c.432G>C synonymous_variant 1.0
katG 2155691 c.421T>C synonymous_variant 1.0
katG 2155696 p.Ala139Gly missense_variant 1.0
katG 2155716 c.396T>G synonymous_variant 1.0
katG 2155728 c.384G>C synonymous_variant 1.0
katG 2155735 p.Met126Gln missense_variant 1.0
katG 2155737 c.375C>A synonymous_variant 0.86
katG 2155743 c.369G>C synonymous_variant 1.0
katG 2155752 c.360C>T synonymous_variant 0.25
katG 2155764 p.His116Ala missense_variant 0.25
katG 2155767 p.Ile115Ala missense_variant 0.33
katG 2155782 c.330C>G synonymous_variant 0.5
katG 2155785 p.Ala109Ser missense_variant 1.0
katG 2155794 c.318G>C synonymous_variant 0.5
katG 2155800 c.312G>C synonymous_variant 1.0
katG 2155806 c.306T>C synonymous_variant 1.0
katG 2155815 c.297G>C synonymous_variant 1.0
katG 2155824 c.288C>G synonymous_variant 0.67
katG 2155836 c.276C>G synonymous_variant 1.0