TB-Profiler result

Run: ERR551075
Summary

Run ID: ERR551075

Sample name:

Date: 15-08-2022 10:45:27

Number of reads: 473803

Percentage reads mapped: 99.79

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575295 c.-53G>A upstream_gene_variant 0.11
mmpL5 776166 p.Asn772Ile missense_variant 0.11
Rv1258c 1406668 c.673T>C synonymous_variant 0.1
Rv1258c 1407182 c.159G>T synonymous_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168738 p.Phe625Leu missense_variant 1.0
pncA 2290202 c.-961C>T upstream_gene_variant 0.15
kasA 2518274 p.Trp54Arg missense_variant 0.12
folC 2746776 p.Gln275* stop_gained 0.15
pepQ 2859864 c.555T>C synonymous_variant 0.09
clpC1 4038169 c.2531_2535delAGCCG frameshift_variant 0.11
clpC1 4038183 p.Gly841Ala missense_variant 0.1
embA 4245363 p.Phe711Leu missense_variant 0.09
aftB 4268845 c.-9T>C upstream_gene_variant 0.11
ubiA 4269482 p.Trp118Arg missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0