TB-Profiler result

Run: ERR551551
Summary

Run ID: ERR551551

Sample name:

Date: 02-08-2023 08:31:10

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6524 p.Arg429Cys missense_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576063 p.His239Arg missense_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474366 n.709T>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154791 p.Pro441Thr missense_variant 0.12
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2169952 p.Asn221Asp missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726241 p.Ala17Thr missense_variant 0.17
Rv2752c 3065318 p.Ala292Thr missense_variant 0.13
fprA 3474136 p.Thr44Ser missense_variant 0.1
fbiA 3640774 p.Gly78Ser missense_variant 0.11
fbiB 3640797 c.-738T>C upstream_gene_variant 0.13
fbiB 3642145 p.Leu204* stop_gained 0.17
clpC1 4039729 p.Asp326Asn missense_variant 1.0
clpC1 4040241 p.Thr155Ile missense_variant 0.1
clpC1 4040249 p.Glu152Asp missense_variant 0.1
embC 4242220 c.2358A>C synonymous_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4246099 p.Phe956Ser missense_variant 0.13
ubiA 4269943 c.-111delG upstream_gene_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0