TB-Profiler result

Run: ERR552643
Summary

Run ID: ERR552643

Sample name:

Date: 15-08-2022 10:45:53

Number of reads: 342238

Percentage reads mapped: 99.71

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6798 p.Gly520Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8215 p.Gln305Arg missense_variant 0.14
mshA 575578 c.231G>C synonymous_variant 1.0
ccsA 620100 c.210G>A synonymous_variant 0.15
rpoB 761743 p.Glu646Gly missense_variant 0.13
rpoC 763520 c.152delT frameshift_variant 0.17
rpoC 766844 p.Arg1159Ser missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776630 c.1851C>T synonymous_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.09
rrl 1475633 n.1976G>A non_coding_transcript_exon_variant 0.1
rpsA 1833732 p.Pro64Leu missense_variant 0.1
ndh 2102202 p.Ser281Thr missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518575 p.Ile154Thr missense_variant 0.2
Rv2752c 3064674 c.1518C>A synonymous_variant 0.18
Rv2752c 3065605 p.Val196Gly missense_variant 0.2
fbiD 3339338 p.Gly74Glu missense_variant 0.14
Rv3083 3448808 p.Leu102Pro missense_variant 0.2
fbiA 3640351 c.-192C>A upstream_gene_variant 0.2
clpC1 4040711 c.-7G>A upstream_gene_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248009 p.Leu499Pro missense_variant 0.11
embB 4249732 c.3219C>G synonymous_variant 1.0
ubiA 4269883 c.-50T>C upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338688 c.-167T>A upstream_gene_variant 0.1
gid 4407793 p.Arg137Gln missense_variant 0.11
gid 4408093 p.Gly37Ala missense_variant 1.0