TB-Profiler result

Run: ERR5979588
Summary

Run ID: ERR5979588

Sample name:

Date: 2024-04-15T11:55:03.580097

Number of reads: 5929551

Percentage reads mapped: 99.96

Median coverage: 190.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mmpR5 779117 p.Leu43Pro missense_variant 0.25 clofazimine
bedaquiline
mmpR5 779285 p.Ala99Val missense_variant 0.11 clofazimine
bedaquiline
mmpR5 779330 p.Leu114Pro missense_variant 0.12 clofazimine
bedaquiline
mmpR5 779351 p.Gly121Glu missense_variant 0.13 clofazimine
bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin