TB-Profiler result

Run: ERR5979592
Summary

Run ID: ERR5979592

Sample name:

Date: 2024-10-04T09:24:00.188850

Number of reads: 8251578

Percentage reads mapped: 99.94

Median coverage: 255.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mshA 576108 p.Ala254Gly missense_variant 0.28 isoniazid
ethionamide
mmpR5 779117 p.Leu43Pro missense_variant 0.24 bedaquiline
clofazimine
mmpR5 779330 p.Leu114Pro missense_variant 0.16 bedaquiline
clofazimine
mmpR5 779351 p.Gly121Glu missense_variant 0.12 bedaquiline
clofazimine
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin