TB-Profiler result

Run: ERR5979774
Summary

Run ID: ERR5979774

Sample name:

Date: 2024-04-14T07:41:47.272866

Number of reads: 7599658

Percentage reads mapped: 99.92

Median coverage: 239.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine mmpR5 p.Ser68Gly Uncertain significance Mutation from literature
para-aminosalicylic_acid
delamanid
bedaquiline mmpR5 p.Ser68Gly Uncertain significance Mutation from literature
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
mmpR5 779191 p.Ser68Gly missense_variant 0.15 clofazimine Uncertain significance Mutation from literature
bedaquiline Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mshA 576108 p.Ala254Gly missense_variant 0.2 ethionamide
isoniazid
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin