TB-Profiler result

Run: ERR5979777
Summary

Run ID: ERR5979777

Sample name:

Date: 2024-10-03T20:15:48.268140

Number of reads: 4612623

Percentage reads mapped: 99.62

Median coverage: 140.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mmpR5 779120 p.Leu44Pro missense_variant 0.11 bedaquiline
clofazimine
mmpR5 779137 p.Arg50Trp missense_variant 0.18 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpR5 779285 p.Ala99Val missense_variant 0.18 bedaquiline
clofazimine
mmpR5 779350 p.Gly121Glu missense_variant 0.17 bedaquiline
clofazimine
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin