TB-Profiler result

Run: ERR5979780
Summary

Run ID: ERR5979780

Sample name:

Date: 02-04-2023 01:23:13

Number of reads: 6854133

Percentage reads mapped: 99.28

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.2
mmpR5 779120 p.Leu44Pro missense_variant 0.15
mmpR5 779126 p.Cys46Tyr missense_variant 0.13
mmpR5 779137 p.Arg50Trp missense_variant 0.27
mmpR5 779348 c.363delG frameshift_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.26
pepQ 2860159 p.Ala87Gly missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.47
rpoA 3878613 c.-106A>C upstream_gene_variant 0.19
rpoA 3878641 c.-134C>G upstream_gene_variant 0.33
embB 4246529 p.Ser6Arg missense_variant 0.22
embB 4246584 p.Arg24Pro missense_variant 0.22