TB-Profiler result

Run: ERR5979786

Summary

Run ID: ERR5979786

Sample name:

Date: 02-04-2023 01:23:07

Number of reads: 5145271

Percentage reads mapped: 99.91

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.22
mmpL5 777883 p.Gly200Arg missense_variant 0.17
mmpR5 779348 c.363delG frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.16
PPE35 2170065 p.Ala183Gly missense_variant 0.13
kasA 2519071 p.Asp319Glu missense_variant 0.2
pepQ 2860159 p.Ala87Gly missense_variant 0.17
fbiD 3339734 p.Ala206Gly missense_variant 0.87
fbiD 3339746 p.Ala210Gly missense_variant 0.2
whiB7 3568431 c.249C>G synonymous_variant 0.19
rpoA 3878641 c.-134C>G upstream_gene_variant 0.64
embC 4240409 p.Pro183Ala missense_variant 0.16
embB 4246584 p.Arg24Pro missense_variant 0.12
embB 4248328 c.1815G>C synonymous_variant 0.17