TB-Profiler result

Run: ERR5979790
Summary

Run ID: ERR5979790

Sample name:

Date: 02-04-2023 01:23:19

Number of reads: 3162301

Percentage reads mapped: 97.95

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.14
mshA 576456 p.Val370Gly missense_variant 0.23
mmpL5 777883 p.Gly200Arg missense_variant 0.16
mmpR5 779137 p.Arg50Trp missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.29
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.33
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.33
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.4
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.4
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.4
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.67
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.43
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.43
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.43
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.43
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.43
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.38
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.38
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.45
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.45
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.42
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.42
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.45
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.45
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.45
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.45
PPE35 2169902 c.711G>C synonymous_variant 0.12
PPE35 2170065 p.Ala183Gly missense_variant 0.18
pepQ 2860159 p.Ala87Gly missense_variant 0.25
fbiD 3339734 p.Ala206Gly missense_variant 1.0
fbiD 3339749 p.Val211Ala missense_variant 0.27
rpoA 3878613 c.-106A>C upstream_gene_variant 0.43
rpoA 3878618 c.-111A>C upstream_gene_variant 0.6
rpoA 3878641 c.-134C>G upstream_gene_variant 0.18
embC 4240409 p.Pro183Ala missense_variant 0.33
embB 4246529 p.Ser6Arg missense_variant 0.23