TB-Profiler result

Run: ERR5979793
Summary

Run ID: ERR5979793

Sample name:

Date: 02-04-2023 01:23:49

Number of reads: 3158608

Percentage reads mapped: 96.73

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.32
mshA 576482 p.Val379Leu missense_variant 0.12
mmpL5 777128 c.1353A>G synonymous_variant 0.11
mmpR5 779263 c.275dupA frameshift_variant&stop_gained 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.13
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.17
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.17
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.17
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.17
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.23
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.21
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.23
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.23
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.14
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.14
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.15
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.15
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.15
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.15
PPE35 2169902 c.711G>C synonymous_variant 0.12
fbiD 3339734 p.Ala206Gly missense_variant 0.2
rpoA 3878637 c.-130G>C upstream_gene_variant 0.17
embB 4246584 p.Arg24Pro missense_variant 0.43