TB-Profiler result

Run: ERR5979799
Summary

Run ID: ERR5979799

Sample name:

Date: 02-04-2023 01:23:51

Number of reads: 3192590

Percentage reads mapped: 97.27

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576482 p.Val379Leu missense_variant 0.19
mmpR5 779285 p.Ala99Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.29
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.56
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.62
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.71
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.71
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.71
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.71
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.71
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.71
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.71
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.71
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.71
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.71
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.62
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.62
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.62
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.62
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.38
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.11
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.11
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.12
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.28
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.24
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.22
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.24
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.22
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.27
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.33
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.29
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.29
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.28
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.29
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.33
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.31
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.38
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.31
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.25
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.14
fbiD 3339734 p.Ala206Gly missense_variant 0.36
rpoA 3878637 c.-130G>C upstream_gene_variant 0.15
embB 4246584 p.Arg24Pro missense_variant 0.31