TB-Profiler result

Run: ERR775807
Summary

Run ID: ERR775807

Sample name:

Date: 02-04-2023 05:43:15

Number of reads: 1052955

Percentage reads mapped: 99.28

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.18
ccsA 620029 c.139C>T synonymous_variant 1.0
ccsA 620383 p.Pro165Ser missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304322 c.1392C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473700 n.43G>C non_coding_transcript_exon_variant 0.1
rrl 1476119 n.2462G>T non_coding_transcript_exon_variant 0.12
inhA 1674631 p.Ile144Val missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747059 c.540T>C synonymous_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 0.32
Rv3083 3448877 p.Thr125Ile missense_variant 0.11
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878350 p.Ser53Asn missense_variant 0.12
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.38
clpC1 4038318 p.Pro796Leu missense_variant 1.0
clpC1 4039484 c.1221T>G synonymous_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268081 c.756A>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0