TB-Profiler result

Run: ERR7764391
Summary

Run ID: ERR7764391

Sample name:

Date: 02-04-2023 05:45:58

Number of reads: 1816396

Percentage reads mapped: 99.59

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576113 p.Arg256Gly missense_variant 0.33
mshA 576482 p.Val379Leu missense_variant 0.22
mshA 576539 p.Trp398Arg missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305354 c.2424C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rpsA 1834852 c.1311C>T synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714846 p.Val163Ile missense_variant 0.2
pepQ 2860159 p.Ala87Gly missense_variant 0.17
fbiD 3339734 p.Ala206Gly missense_variant 0.6
Rv3083 3449085 c.582G>A synonymous_variant 0.11
Rv3236c 3612566 p.Gly184Val missense_variant 1.0
embC 4242437 p.Gln859* stop_gained 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.29
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0