TB-Profiler result

Run: ERR7801143

Summary

Run ID: ERR7801143

Sample name:

Date: 02-04-2023 05:56:16

Number of reads: 36040

Percentage reads mapped: 99.49

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6610 c.-692C>A upstream_gene_variant 1.0
fgd1 491346 c.564C>A synonymous_variant 1.0
rpoB 760583 p.Asp259Glu missense_variant 1.0
rpoC 763431 p.Arg21Met missense_variant 1.0
mmpL5 776574 p.Ala636Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473453 n.-205G>T upstream_gene_variant 1.0
rrl 1475863 n.2206G>T non_coding_transcript_exon_variant 0.67
rpsA 1833584 p.Asp15Asn missense_variant 1.0
katG 2156552 c.-441C>T upstream_gene_variant 1.0
PPE35 2170664 c.-52C>T upstream_gene_variant 1.0
PPE35 2170666 c.-54G>T upstream_gene_variant 1.0
kasA 2519320 p.Phe402Leu missense_variant 1.0
eis 2715395 c.-63C>T upstream_gene_variant 0.67
pepQ 2860158 c.261C>A synonymous_variant 1.0
ribD 2987324 c.486G>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877859 p.Glu217* stop_gained 0.5
embA 4243761 p.Leu177Met missense_variant 0.67
embB 4248097 c.1584C>A synonymous_variant 1.0
whiB6 4338677 c.-156G>A upstream_gene_variant 0.5