TB-Profiler result

Run: ERR7801150
Summary

Run ID: ERR7801150

Sample name:

Date: 02-04-2023 05:56:33

Number of reads: 32096

Percentage reads mapped: 88.55

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8195 c.894C>A synonymous_variant 0.4
fgd1 491280 c.498C>T synonymous_variant 1.0
fgd1 491326 p.Ala182Ser missense_variant 0.67
mshA 575820 p.Ser158* stop_gained 1.0
rpoC 763333 c.-37G>A upstream_gene_variant 0.5
rpoC 767083 c.3714C>T synonymous_variant 1.0
mmpL5 776462 c.2019G>T synonymous_variant 0.67
mmpL5 776483 p.Met666Ile missense_variant 1.0
fbiC 1303818 c.888C>T synonymous_variant 1.0
rrl 1474239 n.582G>T non_coding_transcript_exon_variant 0.67
rrl 1474642 n.985G>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155086 c.1026G>A synonymous_variant 0.67
PPE35 2168434 p.Gly727Trp missense_variant 1.0
PPE35 2169776 p.Phe279Leu missense_variant 0.67
Rv1979c 2222226 c.939C>T synonymous_variant 1.0
kasA 2519236 p.Glu374Asp missense_variant 1.0
kasA 2519255 p.Asp381Tyr missense_variant 1.0
eis 2714645 p.Arg230Cys missense_variant 1.0
thyX 3067229 c.717C>T synonymous_variant 1.0
thyA 3073838 p.His212Asn missense_variant 0.5
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449692 c.1189C>T synonymous_variant 0.67
ddn 3987264 p.Asp141Tyr missense_variant 0.67
embC 4240681 c.819G>T synonymous_variant 1.0
embA 4245359 c.2127G>T synonymous_variant 0.5
embB 4247359 c.846G>T synonymous_variant 0.67
embB 4248028 c.1515C>A synonymous_variant 0.67
embB 4248228 p.Trp572Leu missense_variant 0.67
aftB 4269522 c.-686C>A upstream_gene_variant 0.67
ethR 4326583 c.-966G>T upstream_gene_variant 1.0
gid 4408439 c.-237G>A upstream_gene_variant 1.0