TB-Profiler result

Run: ERR8025352
Summary

Run ID: ERR8025352

Sample name:

Date: 02-04-2023 07:20:03

Number of reads: 1692080

Percentage reads mapped: 99.56

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 620725 p.Leu279Met missense_variant 0.12
rpoB 761279 c.1473C>T synonymous_variant 0.14
rpoB 761287 p.Leu494Arg missense_variant 0.12
rpoC 763375 c.6C>T synonymous_variant 0.14
rpoC 764535 p.Arg389Pro missense_variant 0.38
mmpL5 777883 p.Gly200Arg missense_variant 0.17
fbiC 1305030 c.2100G>T synonymous_variant 0.13
embR 1416430 c.918G>C synonymous_variant 0.21
embR 1417006 c.342G>T synonymous_variant 0.15
rrl 1476058 n.2401T>G non_coding_transcript_exon_variant 0.29
rrl 1476413 n.2756A>T non_coding_transcript_exon_variant 0.2
rpsA 1834659 p.Phe373Tyr missense_variant 0.12
katG 2154130 p.Leu661Gln missense_variant 0.13
pepQ 2860159 p.Ala87Gly missense_variant 0.27
ribD 2987316 p.Ala160Ser missense_variant 0.17
Rv2752c 3065755 p.Val146Ala missense_variant 0.12
ald 3087367 p.Ala183Glu missense_variant 1.0
ald 3087792 p.Ala325Ser missense_variant 0.17
fbiD 3339749 p.Val211Gly missense_variant 0.4
ddn 3987070 p.Ala76Glu missense_variant 1.0
clpC1 4039680 p.Phe342Tyr missense_variant 0.13
embA 4243201 c.-32G>T upstream_gene_variant 0.2
embA 4243682 c.450T>G synonymous_variant 0.25
embB 4248328 c.1815G>C synonymous_variant 0.23
aftB 4267790 c.1047G>A synonymous_variant 0.12
aftB 4268539 p.Leu100Met missense_variant 0.11