TB-Profiler result

Run: ERR8025353
Summary

Run ID: ERR8025353

Sample name:

Date: 2025-03-09T17:41:25.486455

Number of reads: 7139374

Percentage reads mapped: 99.98

Median coverage: 197.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 p.Gln88Glu Mutation from literature
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491044 p.Gln88Glu missense_variant 0.56 delamanid Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
ald 3087367 p.Ala183Glu missense_variant 1.0 cycloserine Uncertain significance
ddn 3987070 p.Ala76Glu missense_variant 0.34 delamanid Uncertain significance
pretomanid Uncertain significance
embB 4247028 p.Leu172Arg missense_variant 0.18 ethambutol Uncertain significance