TB-Profiler result

Run: ERR8774195
Summary

Run ID: ERR8774195

Sample name:

Date: 02-04-2023 08:25:03

Number of reads: 657048

Percentage reads mapped: 99.7

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 762215 p.Lys803Asn missense_variant 0.18
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrl 1475514 n.1857G>T non_coding_transcript_exon_variant 0.33
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.4
inhA 1674847 p.Gln216Glu missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.34
PPE35 2170053 p.Thr187Ser missense_variant 0.34
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726616 p.Asn142His missense_variant 0.2
Rv2752c 3064623 c.1569C>A synonymous_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474598 p.Gly198Trp missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 0.96
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4244087 c.855G>A synonymous_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
embB 4249678 c.3165C>A synonymous_variant 1.0
ubiA 4269467 p.Asn123His missense_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0