TB-Profiler result

Run: ERR8975153
Summary

Run ID: ERR8975153

Sample name:

Date: 02-04-2023 08:42:05

Number of reads: 2866749

Percentage reads mapped: 99.73

Strain: lineage4.9;lineage4.8.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.13
lineage4.9 Euro-American (H37Rv-like) T1 None 0.86
lineage4.8.1 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.16
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5389 c.150C>A synonymous_variant 0.93
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576394 c.1047G>A synonymous_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.11
pepQ 2859843 c.576G>T synonymous_variant 0.12
pepQ 2859890 p.Glu177* stop_gained 0.2
fbiB 3642128 c.594C>A synonymous_variant 0.4
fbiB 3642874 p.Leu447Arg missense_variant 0.1
clpC1 4040027 c.678C>T synonymous_variant 0.15
embA 4244375 c.1143C>A synonymous_variant 0.17
embA 4246468 p.Ile1079Thr missense_variant 0.92
whiB6 4338595 c.-75delG upstream_gene_variant 1.0