TB-Profiler result

Run: ERR8975190
Summary

Run ID: ERR8975190

Sample name:

Date: 02-04-2023 08:43:46

Number of reads: 2629684

Percentage reads mapped: 99.7

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490597 c.-186G>A upstream_gene_variant 0.15
mshA 576779 p.Val478Met missense_variant 0.29
mmpL5 776546 p.Met645Ile missense_variant 1.0
rplC 801355 p.His183Tyr missense_variant 1.0
fbiC 1304322 p.Ser464Arg missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2170183 p.Trp144Arg missense_variant 0.2
eis 2715531 c.-199C>T upstream_gene_variant 0.15
ribD 2987189 c.351G>A synonymous_variant 0.13
Rv3236c 3612017 p.Pro367Leu missense_variant 0.12
Rv3236c 3612093 p.Gly342Arg missense_variant 0.22
Rv3236c 3612142 c.975T>C synonymous_variant 0.17
embC 4241222 p.Gly454Arg missense_variant 0.67
embB 4246610 p.Ala33Thr missense_variant 0.12
ubiA 4269903 c.-70C>T upstream_gene_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0