TB-Profiler result

Run: ERR9125376

Summary

Run ID: ERR9125376

Sample name:

Date: 02-04-2023 11:16:06

Number of reads: 110211

Percentage reads mapped: 99.07

Strain: lineage4.6

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 0.06
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765044 p.Met559Leu missense_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800793 c.-16G>A upstream_gene_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472816 n.971A>C non_coding_transcript_exon_variant 0.29
PPE35 2169854 c.759T>G synonymous_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3087673 p.His285Pro missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642693 p.Ala387Ser missense_variant 1.0
alr 3841506 c.-86A>C upstream_gene_variant 0.5
aftB 4267068 p.Asn590Thr missense_variant 0.5
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0