Run ID: ERR9806720
Sample name:
Date: 21-05-2023 01:38:35
Number of reads: 135930
Percentage reads mapped: 99.51
Strain: lineage4.9
Drug-resistance: HR-TB
Drug | Resistance | Supporting mutations |
---|---|---|
Rifampicin | ||
Isoniazid | R | inhA p.Ser94Ala (1.00) |
Ethambutol | ||
Pyrazinamide | ||
Streptomycin | ||
Fluoroquinolones | ||
Moxifloxacin | ||
Ofloxacin | ||
Levofloxacin | ||
Ciprofloxacin | ||
Aminoglycosides | ||
Amikacin | ||
Capreomycin | ||
Kanamycin | ||
Cycloserine | ||
Ethionamide | R | inhA p.Ser94Ala (1.00) |
Clofazimine | ||
Para-aminosalicylic_acid | ||
Delamanid | ||
Bedaquiline | ||
Linezolid |
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | T1 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
inhA | 1674481 | p.Ser94Ala | missense_variant | 1.0 | isoniazid, ethionamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
rrs | 1473351 | n.1506A>G | non_coding_transcript_exon_variant | 0.33 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
katG | 2155950 | c.162C>A | synonymous_variant | 0.33 |
Rv3083 | 3449713 | p.Ala404Thr | missense_variant | 1.0 |
embB | 4246942 | c.429G>A | synonymous_variant | 0.4 |
embB | 4246968 | p.Ser152Tyr | missense_variant | 0.5 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |